Petasitenine

CAT: 0804-HY-142063Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-142063Size:1 Each

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Description

Petasitenine (Fukinotoxin) is a pyrrolizidine alkaloid that can be found in the plant Petasites japonicus, which is a carcinogenic metabolite of neopetasitenine. Petasitenine causes lactate dehydrogenase leakage, and exhibits hepatotoxicity[1].

CAS Number

60102-37-6

Product Name Alternative

Fukinotoxin

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/petasitenine.html

Smiles

C[C@@H]1[C@]2(C(O[C@@]3([H])C(/C(COC([C@](O)([C@@H](C2)C)C)=O)=C\CN(CC3)C)=O)=O)O1

Molecular Formula

C19H27NO7

Molecular Weight

381.42

References & Citations

[1]Yanagi M, et al., Metabolic profiles for the pyrrolizidine alkaloid neopetasitenine and its metabolite petasitenine in humans extrapolated from rat in vivo and in vitro data sets using a simplified physiologically based pharmacokinetic model. J Toxicol Sci. 2021;46 (9) :391-399.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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