Ziltivekimab
CAT:
804-HY-P99505-02
Size:
10 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
Ziltivekimab
- CAS Number: 2226654-05-1
- UNSPSC Description: Ziltivekimab (COR-001) is a humanized monoclonal antibody against IL-6 that effectively reduces serum CRP levels. Ziltivekimab possesses anti-inflammatory activity and can be used in research related to chronic systemic inflammation associated with chronic kidney disease (CKD) and cardiovascular diseases such as atherosclerosis[1][2].
- Target Antigen: Interleukin Related
- Type: Inhibitory Antibodies
- Related Pathways: Immunology/Inflammation
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology; Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/ziltivekimab.html
- Purity: 99.75
- Solubility: 10 mM in DMSO
- Smiles: [Ziltivekimab]
- References & Citations: [1]Kristen L Nowak, et al. A Phase 1 Randomized Dose-Escalation Study of a Human Monoclonal Antibody to IL-6 in CKD. Kidney360. 2020 Dec 4;2(2):224-235.|[2]Ridker PM. From RESCUE to ZEUS: will interleukin-6 inhibition with ziltivekimab prove effective for cardiovascular event reduction? Cardiovasc Res. 2021 Sep 28;117(11):e138-e140.
- Shipping Conditions: Dry Ice
- Storage Conditions: Store at -80°C for 2 years
- Clinical Information: Phase 3