Products for Research Use Only
RegisterLogin

GS-441524

CAT: 0026-B3076-25Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0026-B3076-25Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GS-441524 is the predominant metabolite of remdesivir in blood and is the nucleoside of the prodrug remdesivir. It is phosphorylated to the active triphosphate metabolite which incorporates into RNA. It shows broad spectrum activity in cell based assays against HCV, YFV, DENV-2, Influenza A, Parainfluenza 3 and SARS-CoV viruses with EC₅₀ values ranging from 1.7 μM-27.9 μM. It inhibits SARS-CoV and MERS-CoV infected human airway epithelial cell cultures with EC₅₀ values of 0.18 μM and 0.86 μM respectively. GS-441524 is suggested for the treatment of COVID-19 due to lower toxicity and simpler synthesis when compared to remdesivir.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

Related Products

CatalogName
2669-1GS-9973
2669-5GS-9973
2613-5CAL-101 (GS-1101)
2613-25CAL-101 (GS-1101)

Alternative Products

CatalogName
bs-83389C-01GS-441524
AG167808-01GS 441524

Popular Products