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Mimopezil

CAT: 0804-HY-14795Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-14795Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mimopezil (ZT-1) is an cholinesterase (ChE) inhibitor that rapidly degrades into the active metabolite Huperzine A in water or aqueous organic solvents. After oral administration, Mimopezil is rapidly absorbed but has low bioavailability (0.37%) in rats. However, after metabolism, it is converted into Huperzine A, which accumulates in the blood and exhibits strong activity. Following intravenous administration, Mimopezil reaches higher blood concentrations and is also rapidly metabolized into Huperzine A[1].
CAS Number
180694-97-7
Product Name Alternative
ZT-1
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mimopezil.html
Smiles
CC1=C[C@@]2([H])CC3=C([C@](C1)(/N=C/C4=CC(Cl)=CC(OC)=C4O)/C2=C/C)C=CC(N3)=O
Molecular Formula
C23H23ClN2O3
Molecular Weight
410.89
References & Citations
[1]Li C, et al. A sensitive method for the determination of the novel cholinesterase inhibitor ZT-1 and its active metabolite huperzine A in rat blood using liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2004;18 (6) :651-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

Alternative Products

CatalogName
MBS5777738Mimopezil

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