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Monepantel (Standard)

CAT: 0804-HY-14774R-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14774R-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Monepantel (Standard) is the analytical standard of Monepantel. This product is intended for research and analytical applications. Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.
CAS Number
887148-69-8
Product Name Alternative
AAD1566 (Standard) ; NUZ-001 (Standard)
UNSPSC
12352005
Target
NAChR; Reference Standards
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/monepantel-standard.html
Purity
99.53
Smiles
O=C(N[C@@](C)(C#N)COC1=CC(C#N)=CC=C1C(F)(F)F)C2=CC=C(SC(F)(F)F)C=C2
Molecular Formula
C20H13F6N3O2S
Molecular Weight
473.39
References & Citations
[1]Hess J, et al. Assessment of the nematocidal activity of metallocenyl analogues of monepantel. Dalton Trans. 2016 Nov 28;45 (44) :17662-17671|[2]Bahrami F, et al. Monepantel induces autophagy in human ovarian cancer cells through disruption of the mTOR/p70S6K signalling pathway. Am J Cancer Res. 2014 Sep 6;4 (5) :558-71.|[3]Raza A, et al. Increased expression of ATP binding cassette transporter genes following exposure of Haemonchus contortus larvae to a high concentration of monepantel in vitro. Parasit Vectors. 2016 Sep 29;9 (1) :522.|[4]Stuchlikova, et al. Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo. Chem Biol Interact. 2015 Feb 5;227:63-8. ?
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
No Development Reported

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