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EG00229

CAT: 0804-HY-18333Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-18333Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EG00229 is an inhibitor for VEGF-A and NRP1 interaction with an IC50 of 8 μM. EG00229 inhibits the migration of HUVECS and the phosphorylation of VEGFR2 in endothelial cells. EG00229 exhibits cytotoxicity in cancer cell A549[1].
CAS Number
1018927-63-3
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
N=C(N)NCCC[C@@H](C(O)=O)NC(C1=C(NS(=O)(C2=CC=CC3=NSN=C32)=O)C=CS1)=O
Molecular Formula
C17H19N7O5S3
Molecular Weight
497.57
References & Citations
[1]Jarvis A, et al., Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. J Med Chem. 2010 Mar 11;53 (5) :2215-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
E1119-25mgEG00229
A16237-50EG00229 50mg
A16237-10EG00229 10mg
A16237-5EG00229 5mg
A16237-2EG00229 2mg
A16237-1EG00229 1mg
A16237-100EG00229 100mg
A16237-25EG00229 25mg
A16237-10mM-DEG00229 10mM * 1mL in DMSO

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