FA-Phe-Phe

• UNSPSC Description:

  FA-Phe-Phe is a furylacryloyl (fa)-amino acid derivative, targeting to Angiotensin-converting Enzyme (ACE). FA-Phe-Phe is also a specific substrate of Cathepsin A[1][2].

• Target Antigen:

  Angiotensin-converting Enzyme (ACE)

• Type:

  Peptides

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  others

• Assay Protocol:

  https://www.medchemexpress.com/fa-phe-phe.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC([C@H](CC1=CC=CC=C1)NC([C@@H](NC(/C=C/C2=CC=CO2)=O)CC3=CC=CC=C3)=O)=O

• Molecular Weight:

  432.47

• References & Citations:

  [1]Mayer M, et al. Mapping the active site of angiotensin-converting enzyme by transferred NOE spectroscopy. J Med Chem. 2000 Jun 1;43(11):2093-9.|[2]Ostrowska H, et al. Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme. Biochem Biophys Res Commun. 1997 May 29;234(3):729-32.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  83661-95-4