FA-Phe-Phe

• Description :

  FA-Phe-Phe is a furylacryloyl (fa) -amino acid derivative, targeting to Angiotensin-converting Enzyme (ACE) . FA-Phe-Phe is also a specific substrate of Cathepsin A[1][2].

• UNSPSC :

  12352209

• Target :

  Angiotensin-converting Enzyme (ACE)

• Type :

  Peptides

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/fa-phe-phe.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC([C@H](CC1=CC=CC=C1)NC([C@@H](NC(/C=C/C2=CC=CO2)=O)CC3=CC=CC=C3)=O)=O

• Molecular Formula :

  C25H24N2O5

• Molecular Weight :

  432.47

• References & Citations :

  [1]Mayer M, et al. Mapping the active site of angiotensin-converting enzyme by transferred NOE spectroscopy. J Med Chem. 2000 Jun 1;43 (11) :2093-9.|[2]Ostrowska H, et al. Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme. Biochem Biophys Res Commun. 1997 May 29;234 (3) :729-32.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [83661-95-4]