Products for Research Use Only
RegisterLogin

Indibulin

CAT: 0607-BA2973-10Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0607-BA2973-10Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
204205-90-3
Form
A solid
Molecular Formula
C22H16ClN3O2
Molecular Weight
389.83
Shipping Conditions
Blue ice
Storage Conditions
-20°C.

Chemical Information

Indibulin

Indibulin is a synthetic small molecule with antimitotic and potential antineoplastic activities. Indibulin binds to a site on tubulin that is different from taxane- or Vinca alkaloid-binding sites, destabilizing tubulin polymerization and inducing tumor cell cycle arrest and apoptosis. This agent has been shown to be active against multidrug-resistant (MDR) and taxane- resistant tumor cell lines.

CAS Number204205-90-3
PubChem CID2929
IUPAC Name2-[1-[(4-chlorophenyl)methyl]indol-3-yl]-2-oxo-N-pyridin-4-ylacetamide
Molecular FormulaC22H16ClN3O2
Molecular Weight389.8
XLogP3.9
Topological Polar Surface Area64
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Heavy Atom Count28
Formal Charge0
Complexity558
SMILES
C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)Cl)C(=O)C(=O)NC4=CC=NC=C4
InChI
InChI=1S/C22H16ClN3O2/c23-16-7-5-15(6-8-16)13-26-14-19(18-3-1-2-4-20(18)26)21(27)22(28)25-17-9-11-24-12-10-17/h1-12,14H,13H2,(H,24,25,28)
InChIKey
SOLIIYNRSAWTSQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Indibulin
CAS: 204205-90-3
CID: 2929
Formula: C22H16ClN3O2
MW: 389.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight389.8
XLogP33.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass389.0931045
Monoisotopic Mass389.0931045
Topological Polar Surface Area64 Ų
Heavy Atom Count28
Formal Charge0
Complexity558
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
B3672-5Indirubin
B3672-250Indirubin
B3672-25Indirubin
B3672-100Indirubin
B3672-5.1Indirubin
B6865-5Indirubin-3'-oxime
B6865-50Indirubin-3'-oxime
B6865-10Indirubin-3'-oxime
BA3841-55-Iodo-indirubin-3-monoxime
BA3841-15-Iodo-indirubin-3-monoxime

Alternative Products

CatalogName
452313-01Indibulin
HY-13649R-01Indibulin (Standard)
A21210-100Indibulin 100mg
A21210-10Indibulin 10mg
A21210-5Indibulin 5mg
A21210-25Indibulin 25mg
A21210-50Indibulin 50mg
A21210-2Indibulin 2mg

Popular Products