cis-KV1.3-IN-1

• CAS Number:

  3052324-05-4

• UNSPSC Description:

  cis-KV1.3-IN-1 (Compound cis-18) is a cis-isomer of KV1.3-IN-1 (HY-155516). cis-KV1.3-IN-1 is an inhibitor of the KV1.3 channel. cis-KV1.3-IN-1 (10 μM) inhibits KV1.3 by 25.53% in Xenopus oocytes expressing human hKV1.3[1].

• Target Antigen:

  Potassium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/cis-kv1-3-in-1.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(O[C@H]1CC[C@@](C2=CSC=C2)(CNC(C3=CC=CC=C3OC)=O)CC1)NCCC

• Molecular Weight:

  430.56

• References & Citations:

  [1]Gubič Š, et al. Immunosuppressive effects of new thiophene-based KV1.3 inhibitors. Eur J Med Chem. 2023 Jun 25;259:115561.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported