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FETUA rabbit pAb

CAT: 0855-ES20407-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES20407-01Size:50 µL
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Background
Function:Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions., polymorphism:There are two common alleles, AHSG*1 and AHSG*2. AHSG*1 has Thr-248/Thr-256; AHSG*2 has Met-248/Ser-256., similarity:Belongs to the fetuin family., similarity:Contains 2 cystatin domains., subunit:Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond., tissue specificity:Synthesized in liver and selectively concentrated in bone matrix. Secrete din plasma. It is also found in dentin in much higher quantities than other plasma proteins.
Description
Function: Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. polymorphism: There are two common alleles, AHSG*1 and AHSG*2. AHSG*1 has Thr-248/Thr-256; AHSG*2 has Met-248/Ser-256. similarity: Belongs to the fetuin family. similarity: Contains 2 cystatin domains. subunit: Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond. tissue specificity: Synthesized in liver and selectively concentrated in bone matrix. Secrete din plasma. It is also found in dentin in much higher quantities than other plasma proteins.
UniProt
P02765
Swiss Prot
P02765
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human FETUA
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
Alpha-2-HS-glycoprotein (Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A) [Cleaved into: Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B]
Gene ID (Human)
197

UniProtKB · P02765

Alpha-2-HS-glycoprotein

FETUA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02765
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AHSG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8K9N6, B2R7G1, O14961, O14962, Q9P152
Protein keywords

Technical term

Direct protein sequencingProteomics identificationReference proteome

Disease

Disease variantHypotrichosisIntellectual disability

PTM

Disulfide bondGlycoproteinPhosphoprotein

Biological process

Mineral balance

Domain

RepeatSignal

Cellular component

Secreted

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