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Byakangelicol

CAT: 0804-HY-N0074-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0074-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Byakangelicol, isolated from Angelica dahurica, inhibits interleukin-1beta (IL-1beta) -induced prostaglandin E2 (PGE2) release in A549 cells mediated by suppression of cyclooxygenase-2 (COX-2) expression and the activity of COX-2 enzyme. Byakangelicol has therapeutic potential as an anti-inflammatory agent on airway inflammation[1].
CAS Number
26091-79-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/byakangelicol.html
Purity
99.87
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C=CC2=C(OC)C3=C(OC=C3)C(OC[C@@H](O4)C4(C)C)=C2O1
Molecular Formula
C17H16O6
Molecular Weight
316.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Lin CH, et al. Byakangelicol, isolated from Angelica dahurica, inhibits both the activity and induction of cyclooxygenase-2 in human pulmonary epithelial cells. J Pharm Pharmacol. 2002 Sep;54 (9) :1271-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2

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