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Midesteine

CAT: 0804-HY-106448-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-106448-01Size:1 mg
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Description
Midesteine (MR 889) is a proteinase inhibitor that can inhibit porcine pancreatic elastase, human neutrophil elastase and bovine chymotrypsin. Midesteine has the potential for chronic obstructive pulmonary disease (COPD) and chronic bronchitis research[1].
CAS Number
94149-41-4
Product Name Alternative
MR 889
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/midesteine.html
Solubility
10 mM in DMSO
Smiles
O=C(SC(C(NC1C(SCC1)=O)=O)C)C2=CC=CS2
Molecular Formula
C12H13NO3S3
Molecular Weight
315.43
References & Citations
[1]M Luisetti, et al. Studies of MR 889, a new synthetic proteinase inhibitor. Biochem Biophys Res Commun. 1989 Dec 15;165 (2) :568-73. |[2]M Luisetti, et al. MR889, a neutrophil elastase inhibitor, in patients with chronic obstructive pulmonary disease: a double-blind, randomized, placebo-controlled clinical trial. Eur Respir J. 1996 Jul;9 (7) :1482-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

Alternative Products

CatalogName
MBS5810652midesteine

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