Heparin (sodium salt)

Heparin (sodium salt)

• CAS Number: 9041-08-1
• UNSPSC Description: Heparin sodium salt (Sodium heparin) is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. Heparin sodium salt significantly inhibits exosome-cell interactions.
• Target Antigen: Autophagy; Factor Xa; Thrombin
• Type: Reference compound
• Related Pathways: Autophagy;Metabolic Enzyme/Protease
• Field of Research: Cardiovascular Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/Heparin-sodium-salt.html
• Solubility: H2O : 100 mg/mL (ultrasonic)
• Smiles: O[C@H]1[C@H](O[C@H]2[C@H](OS(O)(=O)=O)[C@@H](O)[C@H](OC)[C@H](C(O)=O)O2)[C@@H](COS(O)(=O)=O)O[C@H](OC)[C@@H]1NS(O)(=O)=O.[n].[.xNa]
• Molecular Weight: 6117(Average)
• References & Citations: [1]Capila I, et al. Heparin-protein interactions. Angew Chem Int Ed Engl. 2002 Feb 1;41(3):391-412.|[2]Anurag Purushothaman, et al. Fibronectin on the Surface of Myeloma Cell-derived Exosomes Mediates Exosome-Cell Interactions. J Biol Chem. 2016 Jan 22;291(4):1652-63.
• Shipping Conditions: Room Temperature
• Clinical Information: Launched