Products for Research Use Only
RegisterLogin

Furowanin A

CAT: 0804-HY-N3913-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N3913-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Furowanin A is a flavonoid with anti-neoplastic effects. Furowanin A inhibits STAT3/Mcl-1 axis to suppress proliferation, block cell cycle progression, induce apoptosis and promote autophagy. Furowanin A potently inhibits colorectal cancer (CRC) cells[1].
CAS Number
911004-72-3
UNSPSC
12352005
Target
Bcl-2 Family; STAT
Type
Natural Products
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/furowanin-a.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C2=CC=C(O)C(O)=C2)=COC3=C(C/C=C(C)\C)C(OC(C(C)(O)C)C4)=C4C(O)=C13
Molecular Formula
C25H26O7
Molecular Weight
438.47
References & Citations
[1]Ma Z, et al. Furowanin A-induced autophagy alleviates apoptosis and promotes cell cycle arrest via inactivation STAT3/Mcl-1 axis in colorectal cancer. Life Sci. 2019 Feb 1;218:47-57.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Mcl-1; STAT3

Alternative Products

CatalogName
TBW00520Furowanin A

Popular Products