ChTX-Lq2

• UNSPSC Description:

  ChTX-Lq2 is a Ca2+-activated K+ efflux inhibitor with a Kd of 43 nM[1].

• Target Antigen:

  Others

• Type:

  Peptides

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/chtx-lq2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@H](N)CCC(N)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H]1CCCCN)=O)=O)CCCNC(N)=N)=O)CC(N)=O)=O)[C@@H](C)O)=O)CC(N)=O)=O)CC2=CNC=N2)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCCCN)=O)CSSC[C@H](NC3=O)C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CC4=CC=C(O)C=C4)=O)=O)[C@H](CC)C)=O)CO)=O)CC5=CNC6=CC=CC=C56)=O)CSSC[C@H](NC7=O)C(N[C@H]3CCCNC(N)=N)=O)=O)CCC(N)=O)=O)CC(N)=O)=O)CO)=O)C)=O)[C@@H](C)O)=O)CSSC[C@H](NC1=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]7CCCCN)=O)CCCCN)=O)CC(N)=O)=O)CCSC)=O)=O)CO)=O)CCC(O)=O)=O)CCC(N)=O)=O)[C@@H](C)O)=O)CC8=CC=CC=C8

• Molecular Weight:

  4352.94

• References & Citations:

  [1]Lucchesi K, et al. Analysis of the blocking activity of charybdotoxin homologs and iodinated derivatives against Ca2+-activated K+ channels. J Membr Biol. 1989 Aug;109(3):269-81.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported