Hydrangenol

• UNSPSC Description:

  Hydrangenol is an orally active antiphotoaging compound. It can be isolated from Hydrangea serrata leaves. Hydrangenol prevents wrinkle formation by reducing MMP and inflammatory cytokine expression and increasing moisturizing factors and antioxidant genes level[1].

• Target Antigen:

  COX; ERK; Interleukin Related; Keap1-Nrf2; MMP; p38 MAPK

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation;MAPK/ERK Pathway;Metabolic Enzyme/Protease;NF-κB;Stem Cell/Wnt

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/hydrangenol.html

• Purity:

  99.33

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(O)C=CC=C2CC(C3=CC=C(O)C=C3)O1

• Molecular Weight:

  256.25

• References & Citations:

  [1]Myung DB, et al. Hydrangenol Isolated from the Leaves of Hydrangea serrata Attenuates Wrinkle Formation and Repairs Skin Moisture in UVB-Irradiated Hairless Mice. Nutrients. 2019 Oct 2;11(10):2354.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  480-47-7