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Hydrangenol

CAT: 0804-HY-N4028-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N4028-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hydrangenol is an orally active antiphotoaging compound. It can be isolated from Hydrangea serrata leaves. Hydrangenol prevents wrinkle formation by reducing MMP and inflammatory cytokine expression and increasing moisturizing factors and antioxidant genes level[1].
CAS Number
480-47-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX; ERK; Interleukin Related; Keap1-Nrf2; MMP; p38 MAPK
Type
Natural Products
Related Pathways
Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hydrangenol.html
Purity
99.63
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(O)C=CC=C2CC(C3=CC=C(O)C=C3)O1
Molecular Formula
C15H12O4
Molecular Weight
256.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Myung DB, et al. Hydrangenol Isolated from the Leaves of Hydrangea serrata Attenuates Wrinkle Formation and Repairs Skin Moisture in UVB-Irradiated Hairless Mice. Nutrients. 2019 Oct 2;11 (10) :2354.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2; IL-6; MMP-1; MMP-3

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