C-Reactive, Human (HEK293, solution)

C-Reactive, Human (HEK293, solution)

• UNSPSC Description: C-Reactive Protein, an acute-phase protein, is a marker of inflammatory cytokines that assists in complement binding and phagocytosis by macrophages, originated from the liver. C-Reactive Protein is also the first pattern recognition receptor (PRR) to be identified. C-Reactive Protein is significantly associated with the risk of having a first ischemic stroke, especially for small-vessel disease. C-Reactive Protein (Human, solution) is a recombinant protein with tag free and is expressed in HEK293[1][2][3][4][5][6][7][8][9][10][11].
• Target Antigen: Bacterial; Complement System
• Type: Recombinant Proteins
• Related Pathways: Anti-infection;Immunology/Inflammation
• Assay Protocol: https://www.medchemexpress.com/cytokines/c-reactive-protein-protein-human-hek293.html
• Purity: 98.0
• Molecular Weight: Approximately 26 kDa
• References & Citations: [1]Abdullateef Abdullah Z, et al. Role of Serum Ferritin, D-Dimer, and C-Reactive Protein Parameters in COVID 19 Severity. Arch Razi Inst. 2023 Apr 30;78(2):737-742.|[2]Thompson D, et al. The physiological structure of human C-reactive protein and its complex with phosphocholine. Structure. 1999 Feb 15;7(2):169-77. |[3]Pepys MB, et al. C-reactive protein: a critical update. J Clin Invest. 2003 Jun;111(12):1805-12. |[4]Bray C, et al. Erythrocyte Sedimentation Rate and C-reactive Protein Measurements and Their Relevance in Clinical Medicine. WMJ. 2016 Dec;115(6):317-21. |[5]Enocsson H, et al. The Complex Role of C-Reactive Protein in Systemic Lupus Erythematosus. J Clin Med. 2021 Dec 13;10(24):5837.|[6]Sheriff A. Special Issue "C-Reactive Protein and Cardiovascular Disease: Clinical Aspects". J Clin Med. 2022 Jun 22;11(13):3610. |[7]Chen W, et al. Association of C-reactive protein gene polymorphisms with the risk of ischemic stroke: A systematic review and meta-analysis. Brain Behav. 2023 Jun;13(6):e2976.|[8]Li X, et al. Lymphocyte-to-C-Reactive Protein Ratio as an Early Sepsis Biomarker for Neonates with Suspected Sepsis. Mediators Inflamm. 2023 May 8;2023:9077787.|[9]Maillard O, et al. C-reactive protein: An easy marker for early differentiation between leptospirosis and dengue fever in endemic area. PLoS One. 2023 May 17;18(5):e0285900.|[10]Yang Z, et al. Unrevealing the shared genetic mechanisms underlying C-reactive protein and schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2023 Aug 30;126:110785.|[11]Andersson J, et al. C-reactive protein is a determinant of first-ever stroke: prospective nested case-referent study. Cerebrovasc Dis. 2009;27(6):544-51.
• Shipping Conditions: Dry Ice
• Storage Conditions: Stored at -80°C for 1 year