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VDM11

CAT: 0804-HY-103339-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103339-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VDM11 is a potent and selective anandamide membrane transporter (AMT) inhibitor[1]. VDM11 inhibits FAAH and MAGL and may act as an alternative FAAH substrate[2].
CAS Number
313998-81-1
UNSPSC
12352005
Hazard Statement
H302-H312-H332-H334
Target
FAAH; MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vdm11.html
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(NC1=CC=C(O)C=C1C)=O
Molecular Formula
C27H39NO2
Molecular Weight
409.60
Precautions
P261-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P362+P364-P501
References & Citations
[1]De Petrocellis L, et al. Overlap between the ligand recognition properties of the anandamide transporter and the VR1 vanilloid receptor: inhibitors of anandamide uptake with negligible capsaicin-like activity. FEBS Lett. 2000 Oct 13;483 (1) :52-6. |[2]Vandevoorde S, Fowler CJ. Inhibition of fatty acid amide hydrolase and monoacylglycerol lipase by the anandamide uptake inhibitor VDM11: evidence that VDM11 acts as an FAAH substrate. Br J Pharmacol. 2005 Aug;145 (7) :885-93.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported