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Atherosperminine

CAT: 0804-HY-N7648-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7648-01Size:1 mg
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Description
Atherosperminine (Atherospermine) is a nature occurring alkaloid, has antiplasmodial activities in vitro, with an IC50 of 5.80 μM. Atherosperminine is a good reductant with the ability to chelate metals. Atherosperminine has scavenging activity towards the free radical DPPH, with an IC50 of 29.56 μg/mL. Atherosperminine exerts a non-specific relaxant effect on the trachealis[1].
CAS Number
5531-98-6
Product Name Alternative
Atherospermine
UNSPSC
12352005
Hazard Statement
H301-H315-H317-H319
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/atherosperminine.html
Solubility
10 mM in DMSO
Smiles
CN(C)CCC1=C2C=CC3=CC=CC=C3C2=C(OC)C(OC)=C1
Molecular Formula
C20H23NO2
Molecular Weight
309.40
Precautions
P261-P264-P270-P272-P280-P302+P352-P305+P351+P338-P330-P362+P364-P405-P501
References & Citations
[1]Ayu Afiqah Nasrullah, et al. Antiplasmodial Alkaloids from the Bark of Cryptocarya nigra (Lauraceae) . Molecules. 2013 Jul; 18 (7) : 8009–8017.|[2]C H Lin, et al. The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma. Eur J Pharmacol. 1993 Jun 11;237 (1) :109-16.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Plasmodium

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CatalogName
379640Atherosperminine

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