Guanfacine-d2 (hydrochloride)
CAT:
804-HY-17416S-02
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Guanfacine-d2 (hydrochloride)
- CAS Number: 1398065-88-7
- UNSPSC Description: Guanfacine-d2 (hydrochloride) is the deuterium labeled Guanfacine hydrochloride. Guanfacine hydrochloride, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors[1][2].
- Target Antigen: Adrenergic Receptor; Isotope-Labeled Compounds
- Type: Isotope-Labeled Compounds
- Related Pathways: GPCR/G Protein;Neuronal Signaling;Others
- Field of Research: Cardiovascular Disease; Endocrinology
- Solubility: 10 mM in DMSO
- Smiles: N=C(N)NC(C([2H])([2H])C1=C(C=CC=C1Cl)Cl)=O.Cl
- Molecular Weight: 284.57
- References & Citations: [1]Wang J, et al. Huperzine a improves chronic inflammation and cognitive decline in rats with cerebral hypoperfusion. J Neurosci Res. 2010 Mar;88(4):807-15.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported