5-Aminolevulinic acid-13C (hydrochloride)

5-Aminolevulinic acid-13C (hydrochloride)

• UNSPSC Description: 5-Aminolevulinic acid-13C (hydrochloride) is the 13C labeled 5-Aminolevulinic acid hydrochloride[1]. 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles[2][3].
• Target Antigen: Apoptosis; Autophagy; Endogenous Metabolite; Mitophagy
• Type: Isotope-Labeled Compounds
• Related Pathways: Apoptosis;Autophagy;Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/5-aminolevulinic-acid-13c-hydrochloride.html
• Solubility: 10 mM in DMSO
• Smiles: OC(CCC([13CH2]N)=O)=O.Cl
• Molecular Weight: 168.58
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol, 2006. 7(5): p. 392-401.|[3]Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012. 7(9): p. e44885.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported