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Isovaleramide

CAT: 0804-HY-B1229-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1229-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Isovaleramide (3-Methylbutanamide) is an orally active anticonvulsant. Isovaleramide inhibits alcohol dehydrogenase (ADH) activity and regulates GABAergic system. Isovaleramide reduces acute kidney injury. Isovaleramide has antiepileptic, anxiolytic, sedative and hypnotic effects[1][2][3][4].
CAS Number
541-46-8
Product Name Alternative
3-Methylbutanamide
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
GABA Receptor
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Isovaleramide.html
Purity
98.0
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
CC(C)CC(N)=O
Molecular Formula
C5H11NO
Molecular Weight
101.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Giraldo SE, et al. Isovaleramida, principio anticonvulsivo aislado de Valeriana pavonii [Isovaleramide, an anticonvulsant molecule isolated from Valeriana pavonii]. Biomedica. 2010 Apr-Jun;30 (2) :245-50.|[2]Yang K, et al. Isovaleramide attenuates ethylene glycol poisoning‐induced acute kidney injury and reduces mortality by inhibiting alcohol dehydrogenase activity in rats[J]. Basic & Clinical Pharmacology & Toxicology, 2024.|[3]Park H J, et al. Studies on the components of valerian and isovaleramide[J]. YAKHAK HOEJI, 2010, 54 (1) : 1-7.|[4]Manavi M A. Exploring Valeriana species: Unraveling anticonvulsant potential through phytochemistry and pharmacology. Future Natural Products, 2024, 9 (2) : 100-110.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 2

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