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Rimexolone

CAT: 0804-HY-B1754Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1754Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rimexolone (Org 6216) is a glucocorticoid steroid with anti-inflammatory activity. Rimexolone can be used as a 1% ophthalmic suspension for the management of ocular inflammation[1][2].
CAS Number
49697-38-3
Product Name Alternative
Org 6216; Rimexel
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rimexolone.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](C(CC)=O)(C)[C@H](C)C[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O
Molecular Formula
C24H34O3
Molecular Weight
370.52
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Joosten LA, et al. Protective effect of rimexolone on cartilage damage in arthritic mice: a comparative study with triamcinolone hexacetonide. Agents Actions. 1990 Aug;31 (1-2) :135-42.|[2]Foster CS, et al. Efficacy and safety of rimexolone 1% ophthalmic suspension vs 1% prednisolone acetate in the treatment of uveitis. Am J Ophthalmol. 1996 Aug;122 (2) :171-82.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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CatalogName
T34328-01Rimexolone

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