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MHC00188

CAT: 0804-HY-158001Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-158001Size:1 Each
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Description
MHC00188 is an allosteric inhibitor for Autotaxin (ATX) with an IC50 of 2.53 μM[1].
CAS Number
1380881-85-5
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Others
Assay Protocol
https://www.medchemexpress.com/mhc00188.html
Solubility
10 mM in DMSO
Smiles
CC1=C(SC(NC2=CC=CC(C3CCCN3C(C4=NNC5=C4CCCC5)=O)=N2)=N1)C
Molecular Formula
C22H26N6OS
Molecular Weight
422.55
References & Citations
[1]Stylianaki EA, et al., Identification of two novel chemical classes of Autotaxin (ATX) inhibitors using Enalos Asclepios KNIME nodes. Bioorg Med Chem Lett. 2024 Mar 5;103:129690.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Autotaxin

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