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Phospho-mTOR (Ser2448) Rabbit mAb

CAT: 0013-GTR18244504-01Size: 20 ulDry Ice: NoHazardous: No
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CAT#:0013-GTR18244504-01Size:20 ul
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Description
Phospho-mTOR (Ser2448) Rabbit mAb
Product Name Alternative
MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar
UniProt
P42345
Reactivity
Human, Mouse
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser2448 of human mTOR
Target
MTOR
Clonality
Monoclonal
Clone
BT20X9I9
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Affinity Purified
Concentration
0.3 mg/ml
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100
Form
Liquid
Molecular Weight
Calculated MW: 289 kDa; Observed MW: 289 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IHC-P, WB
Preservative
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% rAlbumin.
Isotype
IgG

UniProtKB · P42345

Serine/threonine-protein kinase mTOR

MTOR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P42345
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MTOR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmCytoplasmic vesicleEndoplasmic reticulumGolgi apparatusLysosomeMembraneMicrosomeMitochondrionMitochondrion outer membraneNucleus

Disease

Disease variantEpilepsyIntellectual disability

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

Domain

RepeatTPR repeat

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