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Phospho-IRE1 (Ser724) Rabbit mAb

CAT: 0013-GTR18243843-01Size: 20 ulDry Ice: NoHazardous: No
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CAT#:0013-GTR18243843-01Size:20 ul
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phospho-IRE1 (Ser724) Rabbit mAb
Product Name Alternative
ERN1; IRE1; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a
UniProt
O75460
Reactivity
Human
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser724 of human IRE1
Target
ERN1
Clonality
Monoclonal
Clone
BT27X8G9
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Affinity Purified
Concentration
0.3 mg/ml
Dilution
WB: 1/500-1/1000 IP: 1/20
Form
Liquid
Molecular Weight
Calculated MW: 110 kDa; Observed MW: 110 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IP, WB
Preservative
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% rAlbumin.
Isotype
IgG

UniProtKB · O75460

Serine/threonine-protein kinase/endoribonuclease IRE1

ERN1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75460
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ERN1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A1L457, A8K8N8, A8MXS7, Q59EE2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

ADP-ribosylationDisulfide bondGlycoproteinPhosphoprotein

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisTranscriptionTranscription regulationUnfolded protein response

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Cellular component

Endoplasmic reticulumMembrane

Molecular function

HydrolaseKinaseMultifunctional enzymeSerine/threonine-protein kinaseTransferase

Domain

SignalTransmembraneTransmembrane helix

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