Products for Research Use Only
RegisterLogin

Nauclefine

CAT: 0804-HY-N10149Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N10149Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Nauclefine is an indole alkaloid isolated from Nauclea officinalis. Nauclefine acts as a PDE3A modulator to induce cancer cell apoptosis through a PDE3A-SLFN12-dependent death pathway[1].
CAS Number
57103-51-2
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Apoptosis; Phosphodiesterase (PDE)
Type
Natural Products
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nauclefine.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C=C3C4=C(CCN13)C5=C(C=CC=C5)N4)C=CN=C2
Molecular Formula
C18H13N3O
Molecular Weight
287.32
Precautions
H315, H319, H320
References & Citations
[1]Youwei Ai, et al. An alkaloid initiates phosphodiesterase 3A-schlafen 12 dependent apoptosis without affecting the phosphodiesterase activity. Nat Commun. 2020 Jun 26;11 (1) :3236.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported

Alternative Products

CatalogName
MBS5788220Nauclefine

Popular Products