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Ccl21a Antibody

CAT: 0800-RQ6955Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6955Size:100 µg
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Description
This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. C-C motif chemokine 21a is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19) .
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 2-5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P84444
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant mouse Ccl21a protein (amino acids S24-G133) was used as the immunogen for the Ccl21a antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Ccl21a antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Ccl21a antibody is available for research use only.
Storage Conditions
After reconstitution, the Ccl21a antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Ccl21a antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE rat lung tissue with Ccl21a antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

UniProtKB · P84444

C-C motif chemokine 21a

CC21A_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P84444
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Ccl21a
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
O09002, O09006, Q3U1J2, Q91V84
Protein keywords

Biological process

ChemotaxisInflammatory response

Molecular function

Cytokine

PTM

Disulfide bond

Technical term

Reference proteome

Cellular component

Secreted

Domain

Signal

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