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CD147 Antibody / Emmprin / Basigin

CAT: 0800-RQ6949Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6949Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Emmprin, extracellular matrix metalloproteinase inducer, also known as Basigin (BSG) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the BSG gene. This protein is a determinant for the Ok blood group system. BSG has been shown to be an essential receptor on red blood cells for the malaria parasite. It is a member of the immunoglobulin superfamily, with a structure related to the putative primordial form of the family. As members of the immunoglobulin superfamily, it plays fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development. BSG is thought also to play a role in intercellular recognition. It also regulates several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. BSG is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins. It is expressed by many cell types, including epithelial cells, endothelial cells and leukocytes.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL
UniProt
P35613
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Recombinant human protein (amino acids E138-A323) was used as the immunogen for the CD147 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
3B13G7
Applications
WB, IHC-P, IF
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the CD147 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CD147 antibody is available for research use only.
Storage Conditions
After reconstitution, the CD147 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CD147 antibody should be determined by the researcher.
Location
Cell surface
Image Legend
IHC staining of FFPE human endometrial cancer tissue with CD147 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Product Datasheet
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