Products for Research Use Only
RegisterLogin

CCR7 Antibody

CAT: 0800-RQ6939Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-RQ6939Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P32248
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human CCR7 protein (amino acids K332-E371) was used as the immunogen for the CCR7 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the CCR7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CCR7 antibody is available for research use only.
Storage Conditions
After reconstitution, the CCR7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CCR7 antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of human U-2 OS cells with CCR7 antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= CCR7 antibody.

Related Products

CatalogName
F53335-0.08MLCCR1 Antibody
RQ5799CCR2 Antibody
F40687-0.4MLCCR8 Antibody
F46222-0.4MLCCR4 Antibody
F53335-0.4MLCCR1 Antibody
RQ4399CCR4 Antibody
R32995CCR5 Antibody
F52866-0.08MLCCR2 Antibody
RQ5653CCR2 Antibody
F48896-0.4MLCCR1 Antibody

Alternative Products

CatalogName
70R-30891CCR7 antibody

Popular Products