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Ku70 (6H10) Mouse mAb

CAT: 0013-GTR18243058-01Size: 20 ulDry Ice: NoHazardous: No
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CAT#:0013-GTR18243058-01Size:20 ul
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Description
Ku70 (6H10) Mouse mAb
Product Name Alternative
XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-
UniProt
P12956
Reactivity
Human
Immunogen
Purified recombinant human Ku70 protein fragments expressed in E.coli.
Target
XRCC6
Clonality
Monoclonal
Clone
B8J32XG1XI9
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Purification
Affinity Purified
Concentration
2.5 mg/ml
Dilution
WB: 1/500-1/1000 IF: 1/50-1/200
Form
Liquid
Molecular Weight
Calculated MW: 70 kDa; Observed MW: 70 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IF, WB
Preservative
Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
Isotype
IgG2b

UniProtKB · P12956

DNA repair protein Ku70

XRCC6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P12956
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
XRCC6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
4.2.99.18, 5.6.2.4
Processing
—
Secondary accessions
B1AHC8, Q6FG89, Q9UCQ2, Q9UCQ3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationADP-ribosylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-bindingHelicaseHydrolaseIsomeraseLyaseMultifunctional enzyme

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

ChromosomeCytoplasmNucleus

Biological process

DNA damageDNA recombinationDNA repairHost-virus interactionImmunityInnate immunityTranscriptionTranscription regulation

Disease

Systemic lupus erythematosus

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