Human Tissue Plasminogen Activator

• Background :

  Tissue plasminogen Activator (abbreviated tPA or PLAT) is a protein involved in the breakdown of blood clots. Specifically, it is a serine protease (EC 3.4.21.68) found on endothelial cells lining the blood vessels. It catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown.

• Description :

  Non disponible

• UniProt :

  P00750

• Endotoxin :

  < 0.1 ng/µg (1 EU/µg), using the LAL gel clot method.

• Purity :

  ≥ 98% by SDS-PAGE and HPLC

• Format :

  Lyophilized protein

• Reconstitution :

  Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.

• Shipping Conditions :

  Gel Packs or Dry Ice

• Storage Conditions :

  The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles.

• Calculated Molecular Weight :

  60 kDa

• Formulation :

  Lyophilized from a 0.2 µm filtered 1 mg/ml solution containing 0.2 M L-arginine, 0.1 M phosphoric acid.