Cilostazol

• Background:

  Cilostazol (OPC-13013, Pletal) is a 2-oxo-quinoline derivative with antithrombotic, vasodilator, antimitogenic and cardiotonic properties. Cilostazol is used in the treatment of peripheral arterial disease and claudication (leg cramps) . Cilostazol inhibits platelet aggregation and is a direct arterial vasodilator.

• Description:

  Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 µM and inhibitor of adenosine uptake.

• Format:

  White to off-white crystals

• Solubility:

  Soluble in DMSO (18 mg/mL) .

• Molecular Formula:

  C20H27N5O2

• Shipping Conditions:

  Room Temperature (continental US) or Gel Packs

• Storage Conditions:

  Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

• Calculated Molecular Weight:

  369.5 Da

• CAS Number:

  73963-72-1