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PYR-41

CAT: 0421-27716-1Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0421-27716-1Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PYR-41 is a cell permeable, irreversible inhibitor of ubiquitin activating enzyme E1 with little or no activity against E2s or E3s (IC50 < 10 μM) . It blocks degradation of p53 and inhibits NF-kappaB-dependent pathways. PYR-41 also increases SUMOylation of proteins.
CAS Number
418805-02-4
Applications
Useful for inhibition of E1 ubiquitin conjugating enzymes
Purity
> 98% by TLC.
Format
Brown powder
Solubility
Soluble in DMSO (100 mM)
Molecular Formula
C17H13N3O7
Shipping Conditions
Room Temperature or Gel Packs
Storage Conditions
Store at +4°C. Stable as supplied for up to 2 years when stored dessicated at +4°C. Store solutions at -20°C for up to 1 week.
Calculated Molecular Weight
371.3 Da

Alternative Products

CatalogName
B1492-25PYR-41
256369-01PYR 41

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