Streptozocin (U-9889)

CAT: 0421-27656-2Size: 500 mgDry Ice: NoHazardous: No
CAT#:0421-27656-2Size:500 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Streptozocin, also known as streptozotocin and U-9889, is a small molecule, N-nitroso-containing antibiotic and a potent DNA methylating agent. Streptozocin acts as a nitric oxide (NO) donor and vasorelaxant. In rat cell studies, this compound presented significant methylation of the liver, kidney, and pancreatic cells and selectivity for these cells against the more general methylating activity of the aglycone analog N-methyl-N-nitrosourea . Streptozocin shows particular activity in the pancreas, and has been used both to induce diabetes in mammals and to treat human pancreatic cancers.
Description
Antibiotic and antitumor agent. Alkylates DNA and induces diabetes mellitus via reduction of nicotinamide adenine dinucleotide in pancreatic β-cells in vivo.
CAS Number
18883-66-4
Purity
≥ 98% by HPLC
Solubility
Soluble in water (50 mg/mL), ethanol (3 mg/mL), and DMSO (50 mg/mL) . Solutions are not stable; release of NO gas occurs spontaneously at room temperature. Prepare solutions immediately before use.
Molecular Formula
C8H15N3O7
Shipping Conditions
Room Temperature (continental US) or Gel Packs
Storage Conditions
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Calculated Molecular Weight
265.2 Da

Alternative Products

CatalogName
sc-200719Streptozotocin (U-9889)
1621/100Streptozocin
MC11104-01Streptozocin (Streptozotocin)
S8051-01Streptozocin, STZ
GC301002-100mgStreptozocin STZ
TBI2127-1GStreptozocin (Streptozotocin), Diabetes inducer
294601-01Streptozocin discontinued. See 045318

Popular Products