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SGC-CBP30

CAT: 0421-27650-2Size: 50 mgDry Ice: NoHazardous: No
CAT#:0421-27650-2Size:50 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CREBBP (CBP) and EP300 are general transcriptional co-activators, which are involved in many biological processes like maintenance of genomic stability by affecting DNA replication and DNA repair as well as cell growth, transformation and development. They also play and essential role in neuronal plasticity/ memory formation hematopoiesis and energy homeostasis as demonstrated in a variety of mouse models. They possess both acetyl-transferase enzymatic and bromodomain containing regions. Through acetylation of non-histone proteins CREBBP can have a positive or negative effect on transcriptional regulation by affecting protein- protein interactions, protein-DNA interactions, nuclear retention or protein half-life.
Description
Potent CREBBP/EP300 bromodomain inhibitorThis product has beencited 1 time.
Purity
≥ 98% by HPLC
Solubility
Soluble in DMSO
Molecular Formula
C28H33ClN4O3
Shipping Conditions
Room Temperature (continental US) or Gel Packs
Storage Conditions
Store at or below +4°C. Solid form is stable at least 12 months from date of receipt, when stored as directed.
Calculated Molecular Weight
509.0 Da

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