Products for Research Use Only
RegisterLogin

NLG919

CAT: 0421-27337-2Size: 50 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0421-27337-2Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NLG919 is an orally available potent inhibitor of the indoleamine-2,3- dioxygenase (IDO1) pathway, a crucial pathway involved in allergic inflammation that mediates immunosuppressive effects through metabolization of tryptophan to kynurenine. NLG919 affects differentiation and proliferation of T cells by inducing downstream signaling via GCN2, mTOR and AHR, with values of Ki = 7 nM and EC50 = 75 nM. NLG919 is being investigated for the treatment of immunosuppression associated with cancer.
CAS Number
1402836-58-1
Purity
≥ 98%
Format
White powder
Solubility
Soluble in DMSO at 15 mg/mL.
Molecular Formula
C18H22N2O
Shipping Conditions
-80°C
Storage Conditions
Store as supplied at or below -20°C for up to 3 years. Stable in DMSO at -80°C for up to 6 months.
Calculated Molecular Weight
282.4 Da

Alternative Products

CatalogName
MBS385794-01NLG919
TRC-N630002-1MGNLG919-d10
A14322-10NLG919 10mg
A14322-500NLG919 500mg
A14322-100NLG919 100mg
A14322-25NLG919 25mg
A14322-50NLG919 50mg
A14322-5NLG919 5mg
A14322-2NLG919 2mg
206165NLG919 (GDC-0919)

Popular Products