Products for Research Use Only

CKIT Assay Kit

CAT: 0421-79815Size: 96 ReactionsDry Ice: YesHazardous: No
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CAT#:0421-79815Size:96 Reactions
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
C‐KIT is a proto‐oncogene and a type III transmembrane receptor for mast cell growth factor, also known as stem cell factor. It plays an essential role in the regulation of cell survival and proliferation, as well as hematopoiesis, stem cell maintenance, gametogenesis, melanogenesis, and mast cell development, migration and function. Activating mutations in cKIT are associated with gastrointestinal stromal tumors, testicular seminoma, mast cell disease, melanoma, and acute myeloid leukemia, while inactivating mutations are associated with the genetic defect piebaldism.
Description
The cKIT Assay Kit is designed to measure cKIT activity for screening and profiling applications using ADP-Glo® Kinase Assay as a detection reagent.This product has beencited 2 times.
UniProt
P10721
Format
CatalogNumberReagentAmountStorage40250cKit, His-Tag20 µg-80°CAvoidmultiplefreeze/thawcycles!793345x Kinase Assay Buffer 11.5 ml-20°C79686ATP (500 μM) 100 µl-20°C40217Protein Tyrosine Kinase Substrate (Poly-Glu, Tyr 4:1) (10 mg/ml) 100 µl-20°C7969696-well plate, white1Room Temp.
Shipping Conditions
-80°C
Storage Conditions
Up to 6 months when stored as recommended.