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TMPRSS2 – Vero E6 Recombinant Cell Line

CAT: 0421-78081Size: 2 VialsDry Ice: YesHazardous: No
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CAT#:0421-78081Size:2 Vials
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Human transmembrane serine protease 2 (TMPRSS2) is an enzyme primarily expressed by endothelial cells across the respiratory and digestive tracts. It is involved in viral entry and spread of coronaviruses including SARS-CoV-2, the virus that causes COVID-19. Blocking TMPRSS2 could potentially be an effective clinical therapy for COVID-19.
Description
Recombinant clonal stable Vero E6 cell line constitutively expressing full length human TMPRSS2 (Genbank #NM_005656.4) .This product has beencited 45 times.Purchase of this cell line is for research purposes only; commercial use requires a separate license. View thefull terms and conditions.
CAS Number
9000-83-3
UniProt
O15393
Applications
Screen human TMPRSS2 inhibitors
Shipping Conditions
-80°C
Storage Conditions
Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.
Notes
This cell line may require a CITES certificate for export, which can incur additional fees.  Please contact BPS Bioscience [email protected] your local distributor for more information.License DisclosureVisitbpsbioscience.com/licensefor the label license and other key information about this product.Troubleshooting GuideVisitbpsbioscience.com/cell-line-faqfor detailed troubleshooting instructions. For all further questions, please email[email protected].

UniProtKB · O15393

Transmembrane protease serine 2

TMPS2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15393
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TMPRSS2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.122
Processing
Precursor
Secondary accessions
A8K6Z8, B2R8E5, B7Z459, D3DSJ2, F8WES1, Q6GTK7, Q9BXX1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Autocatalytic cleavageDisulfide bondGlycoproteinZymogen

Cellular component

Cell membraneMembraneSecreted

Biological process

Host-virus interaction

Molecular function

HydrolaseProteaseSerine protease

Domain

Signal-anchorTransmembraneTransmembrane helix

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