DPY30, His-tag Recombinant

• Background:

  As part of the MLL1/MLL complex, involved in the methylation of histone H3 at Lys-4, particularly trimethylation. Histone H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 Lys-4 methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.

• Description:

  Non disponible

• UniProt:

  Q9C005

• Tag:

  N-terminal His-tag

• Purity:

  ≥ 90%

• Format:

  Aqueous buffer solution

• Shipping Conditions:

  -80°C

• Storage Conditions:

  At least 6 months at -80°C.

• Calculated Molecular Weight:

  12 kDa

• Formulation:

  45 mM Tris-HCl pH 8.0,124 mM NaCl, 2.4 mM KCk, 225 mM Imidazole, 1 mM TCEP, 1 µM ZnCl2,10% Glycerol.