CrkL Rabbit Polyclonal Antibody

• Description:

  This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

• Product Name Alternative:

  Crk L antibody Crk like protein antibody Crk-like protein antibody Crkl antibody CRKL_HUMAN antibody Crkol antibody HGNC:2363 antibody Oncogene CrkL antibody V crk avian sarcoma virus CT10 oncogene homolog like antibody v crk sarcoma virus CT10 oncogene homolog (avian) like antibody V crk sarcoma virus CT10 oncogene homolog avian like antibody

• Abbreviation:

  CRKL

• Swiss Prot:

  P46109 Human, P47941 Mouse, Q5U2U2 Rat

• Cellular Locus:

  Cytosol, extrinsic component of postsynaptic membrane, neuromuscular junction, nucleoplasm.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within human CrkL aa 1-303 / 303.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell, FC

• Positive Control:

  K-562 cell lysate, 293T cell lysate, MCF7 cell lysate, Jurkat cell lysate, HT-29 cell lysate, THP-1 cell lysate, HeLa cell lysate, A431 cell lysate, HL-60 cell lysate, C6 cell lysate, mouse thymus tissue lysate, rat thymus tissue lysate, K-562.

• Concentration:

  1.053 mg/mL

• Dilution:

  WB: 1:2,000 ;IF-Cell: 1:100 ;FC: 1:1,000

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 34 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4