Products for Research Use Only
RegisterLogin

Afzelin (Standard)

CAT: 0804-HY-N1441R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N1441R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Afzelin (Standard) is the analytical standard of Afzelin. This product is intended for research and analytical applications. Afzelin (Kaempferol-3-O-rhamnoside) It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1) s level. AfzelinCan be improved D-galactosamine (GalN) /LPSSurvival rate of mice treated with doxorubicin prophylaxis Induced cardiotoxicity and scopolamine (HY-N0296) -induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin[1][2][3][4].
CAS Number
482-39-3
Product Name Alternative
Kaempferol-3-O-rhamnoside (Standard)
UNSPSC
12352005
Target
Autophagy; Bacterial; Mitochondrial Metabolism; PTEN; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Autophagy; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR
Field of Research
Infection; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/afzelin-standard.html
Purity
99.44
Smiles
O=C1C(O[C@H]2[C@@H]([C@@H]([C@H]([C@H](C)O2)O)O)O)=C(C3=CC=C(O)C=C3)OC4=CC(O)=CC(O)=C14
Molecular Formula
C21H20O10
Molecular Weight
432.38
References & Citations
[1]Lee SB, et al. Afzelin ameliorates D-galactosamine and lipopolysaccharide-induced fulminant hepatic failure by modulating mitochondrial quality control and dynamics. Br J Pharmacol. 2017 Jan;174 (2) :195-209.|[2]Oh SY, et al. Central administration of afzelin extracted from Ribes fasciculatum improves cognitive and memory function in a mouse model of dementia. Sci Rep. 2021 Apr 28;11 (1) :9182.|[3]Zhou W, et al. Afzelin attenuates asthma phenotypes by downregulation of GATA3 in a murine model of asthma. Mol Med Rep. 2015 Jul;12 (1) :71-6.|[4]Sun Y, et al. Afzelin protects against doxorubicin-induced cardiotoxicity by promoting the AMPKα/SIRT1 signaling pathway. Toxicol Appl Pharmacol. 2023 Oct 15;477:116687.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

Related Products

CatalogName
HY-N1441-01Afzelin
HY-N16702'',4''-Di-O- (Z-p-Coumaroyl) afzelin
HY-N1669-012'',4''-Di-O- (E-p-Coumaroyl) afzelin
HY-P2274RArgifin (Standard)
HY-N9362REmodinanthrone (Standard)
HY-N7948RIsomaltotetraose (Standard)
HY-N7640RDeoxylimonin (Standard)
HY-N7617RToralactone (Standard)
HY-N7541RAntrodin A (Standard)
HY-N6739RBeauvericin (Standard)

Alternative Products

CatalogName
TA0204550Afzelin
371146Afzelin discontinued
A13891-50Afzelin 50mg
A13891-5Afzelin 5mg
A13891-25Afzelin 25mg
A13891-100Afzelin 100mg
A13891-10Afzelin 10mg
A13891-1Afzelin 1mg
TN27122'',4''-Di-O- (Z-p-coumaroyl) afzelin
MBS57613272'',4''-Di-O-(E-p-coumaroyl)afzelin

Popular Products