Siglec-E, Mouse (HEK293, Fc)

• UNSPSC Description:

  Siglec-E Protein is a mouse orthologue of human Siglec-9 and functions as a key immunosuppressive checkpoint molecule. Siglec-E interacts with CD36 to inhibits downstream VAV signaling involved in modified LDL uptake, thereby delaying atherosclerosis. The endogenous inducible Siglec-E plays crucial anti-inflammatory and neuroprotective roles following ischemic stroke. Siglec-E Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Siglec-E protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-E Protein, Mouse (HEK293, Fc) is 336 a.a..

• Type:

  Recombinant Proteins

• Assay Protocol:

  https://www.medchemexpress.com/cytokines/siglec-e-protein-mouse-hek-293-fc.html

• Purity:

  98.0

• Smiles:

  QNPQEGFTLN VERKVVVQEG LCVLVPCNFS YLKKRLTDWT DSDPVHGFWY REGTDRRKDS IVATNNPIRK AVKETRNRFF LLGEPWRNDC SLNIREIRKK DAGLYFFRLE RGKTKYNYMW DKMTLVVTAL TNTPQILLPE TLEAGHPSNL TCSVPWDCGW TAPPIFSWTG TSVSFLSTNT TGSSVLTITP QPQDHGTNLT CQVTLPGTDV STRMTIRLNV SYAPKNLTVT IYQGADSVST ILKNGSSLPI SEGQSLRLIC STDSYPPANL SWSWDNLTLC PSKLSKPGLL ELFPVHLKHG GVYTCQAQHA LGSQHISLSL SPQSSATLSE MMMGTF

• Molecular Weight:

  Approximately 78-100 kDa due to the glycosylation.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stored at -20°C for 2 years