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MTI013

CAT: 0804-HY-159890Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-159890Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MTI013 is a selective SARS-CoV-2 nsp14 Mtase inhibitor (IC50: 2.98 μM) and an antiviral agent (IC50: 10.33 μM in HCoV-229E-infected Huh7 cells). MTI013 also shows a synergistic antiviral effect with the RdRp inhibitor SHEN26.
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mti013.html
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1CSCC4=CC(C(NC5=CC=CC=C5)=O)=CC=C4
Molecular Formula
C24H24N6O4S
Molecular Weight
492.55
References & Citations
[1]Chen Q, et al. Identification of adenosine analogues as nsp14 N7‑methyltransferase inhibitors for treating coronaviruses infection. Bioorg Chem. 2024 Oct 18;153:107894.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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