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Niguldipine

CAT: 0804-HY-101390BSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101390BSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Niguldipine is a calcium channel blocker with activity in regulating cardiovascular function. Niguldipine can reduce systolic and diastolic blood pressure, thereby increasing heart rate and cardiac output. Niguldipine exhibits dose-dependent and sustained increases in coronary blood flow. Niguldipine also increases perfusion in the kidneys and femoral arteries, but the effect is temporary and to a lesser extent. The effect of Niguldipine on myocardial metabolism is not significant[1].
CAS Number
102993-22-6
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/niguldipine-free-base.html
Smiles
O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OCCCN3CCC(C4=CC=CC=C4)(C5=CC=CC=C5)CC3
Molecular Formula
C36H39N3O6
Molecular Weight
609.71
References & Citations
[1]Effects of niguldipine, a new dihydropyridine calcium antagonist, on regional blood flow, cardiac performance and myocardial metabolism in anaesthetized open-chest dogs
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19273700-01(+) -Niguldipine
C3067-25Niguldipine (hydrochloride)
460757-01Niguldipine Hydrochloride
bs-82139C-01Niguldipine HCl
T23225-01(R) - (-) -Niguldipine
BML-CA216-0050Niguldipine . HCl
464931-01S- (+) -Niguldipine Hydrochloride
GK1940-5mgS (+) -Niguldipine hydrochloride
BUP23741-01Niguldipine Free Base
M33919-01(S) - (+) -Niguldipine hydrochloride

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