Fmoc-Ala-Glu-Gln-Lys-NH2

Fmoc-Ala-Glu-Gln-Lys-NH2

• UNSPSC Description: Fmoc-Ala-Glu-Gln-Lys-NH2 (AEQK) is a tetrapeptide. Fmoc-Ala-Glu-Gln-Lys-NH2 is the inactive control for Fmoc-Ala-Glu-Asn-Lys-NH2 (AENK) peptide inhibitor. AENK blocks proteolysis of UNC5C protein[1].
• Target Antigen: Amino Acid Derivatives
• Type: Peptides
• Related Pathways: Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/fmoc-ala-glu-gln-lys-nh2.html
• Purity: 99.90
• Solubility: DMSO : 3.57 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic;adjust pH to 2 with HCl)
• Smiles: O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N)=O)=O)=O)[C@H](C)NC(OCC1C(C=CC=C2)=C2C3=C1C=CC=C3)=O
• Molecular Weight: 695.76
• References & Citations: [1]Chen G, et al. Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer's disease pathologies. Sci Adv. 2021 Apr 16;7(16):eabe4499.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
• Clinical Information: No Development Reported