Products for Research Use Only

Pafenolol

CAT: 0804-HY-165495-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-165495-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Pafenolol is a selectively oral-active β1 adrenergic receptor (β1-adrenergic receptor) antagonist that effectively lowers blood pressure. Pharmacokinetic studies in rats indicate that the absorption of Pafenolol is influenced by gastrointestinal contents, with food intake reducing the bioavailability of Pafenolol in rats. Pafenolol can be used in research related to cardiovascular diseases and asthma[1].
CAS Number
75949-61-0
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pafenolol.html
Smiles
CC(C)NC(NCCC1=CC=C(C=C1)OCC(O)CNC(C)C)=O
Molecular Formula
C18H31N3O3
Molecular Weight
337.46
References & Citations
[1]Sigurdsson J A, et al. Pafenolol, a new β 1-selective blocking agent, in mild hypertension. Result of an inpatient study and a subsequent outpatient follow-up[J]. European journal of clinical pharmacology, 1984, 26: 549-553.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor

Alternative Products