Ac-IEPD-AMC (TFA)

Ac-IEPD-AMC (TFA)

• UNSPSC Description: Ac-IEPD-AMC TFA is a fluorescent substrate used to measure protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC fluoresces under UV light irradiation and can emit fluorescent signals[1].
• Target Antigen: Fluorescent Dye
• Type: Peptides
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/ac-iepd-amc-tfa.html
• Purity: 98.88
• Solubility: DMSO : 250 mg/mL (ultrasonic)
• Smiles: CC(C1=CC=C(NC([C@H](CC(O)=O)NC([C@H]2N(CCC2)C([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)[C@@H](C)CC)=O)=O)=O)=O)C=C1O3)=CC3=O.OC(C(F)(F)F)=O.[x]
• Molecular Weight: 671.69 (free acid)
• References & Citations: [1]Scott JI, et, al. A Functional Chemiluminescent Probe for in Vivo Imaging of Natural Killer Cell Activity Against Tumours. Angew Chem Int Ed Engl. 2021 Mar 8;60(11):5699-5703. [Content Brief]
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported