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Myelopeptide-2

CAT: 0804-HY-P3736Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P3736Size:1 Each
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Description
Myelopeptide-2 is a peptide originally isolated from the supernatant of porcine bone marrow cell cultures, can restore mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. Myelopeptide-2 also recover depressed interleukin-2 (IL-2) synthesis and interleukin-2 receptor (IL-2R) expression. Myelopeptide-2 involves in immunity homeostasis, is perspective to be applied in antitumor and antivirus research[1][2].
CAS Number
137833-31-9
Product Name Alternative
MP-2
UNSPSC
12352209
Target
Interleukin Related
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/myelopeptide-2.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N2[C@@H](CCC2)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(O)=O)=O)=O)=O)=O)[C@H](CC(C)C)N
Molecular Formula
C41H57N7O8
Molecular Weight
775.93
References & Citations
[1]Mikhailova AA, et al. Myelopeptide-2 recovers interleukin-2 synthesis and interleukin-2 receptor expression in human T lymphocytes depressed by tumor products or measles virus. J Immunother. 2006 May-Jun;29 (3) :306-12. |[2]Mikhailova AA, et al. Effect of myelopeptide-2 on the development of spontaneous and urethane-induced tumors in mice. Bull Exp Biol Med. 2002 Jan;133 (1) :68-70.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
IL-2

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